Vuong Lab at U of MN

Publications

2025

Murine maternal microbiome modifies adverse effects of protein undernutrition on offspring neurobehaviour
Murine maternal microbiome modifies adverse effects of protein undernutrition on offspring neurobehaviour
Elena J. Coley-O’Rourke, Gregory R. Lum, Geoffrey N. Pronovost, Lewis W. Yu, Ezgi Özcan, …, Simone Renwick, Lars Bode, Alison Chu, Kara L. Calkins, Elaine Y. Hsiao
Nature Microbiology  ·  13 Jun 2025  ·  doi:10.1038/s41564-025-02022-7
Select microbial metabolites in the small intestinal lumen regulate vagal activity via receptor-mediated signaling
Select microbial metabolites in the small intestinal lumen regulate vagal activity via receptor-mediated signaling
Kelly G. Jameson, Sabeen A. Kazmi, Takahiro E. Ohara, Celine Son, Kristie B. Yu, …, Jorge Paramo, Arlene Lopez-Romero, Long Yang, Felix E. Schweizer, Elaine Y. Hsiao
iScience  ·  01 Mar 2025  ·  doi:10.1016/j.isci.2025.112059
Interactions of the maternal microbiome with diet, stress, and infection influence fetal development
Interactions of the maternal microbiome with diet, stress, and infection influence fetal development
Chloe H Puglisi, Minjeong Kim, Modi Aldhafeeri, Megan Lewandowski, Helen E. Vuong
The FEBS Journal  ·  23 Feb 2025  ·  doi:10.1111/febs.70031

2024

Host–microbe interactions: communication in the microbiota–gut–brain axis
Host–microbe interactions: communication in the microbiota–gut–brain axis
Aryan Shekarabi, Izhan Qureishy, Chloe H Puglisi, Marge Dalseth, Helen E Vuong
Current Opinion in Microbiology  ·  01 Aug 2024  ·  doi:10.1016/j.mib.2024.102494

2023

The maternal microbiome promotes placental development in mice
The maternal microbiome promotes placental development in mice
Geoffrey N. Pronovost, Kristie B. Yu, Elena J. L. Coley-O’Rourke, Sahil S. Telang, Angela S. Chen, …, Anisha Chandra, Tomiko K. Rendon, Jorge Paramo, Reuben H. Kim, Elaine Y. Hsiao
Science Advances  ·  06 Oct 2023  ·  doi:10.1126/sciadv.adk1887

2022

Crushing it: Indole-3 propionate promotes axonal regeneration in mice
Crushing it: Indole-3 propionate promotes axonal regeneration in mice
Amanda N. Borowski, Helen E. Vuong
Cell Host & Microbe  ·  01 Sep 2022  ·  doi:10.1016/j.chom.2022.08.006
Intersections of the microbiome and early neurodevelopment
Intersections of the microbiome and early neurodevelopment
Helen E. Vuong
International Review of Neurobiology  ·  09 Jul 2022  ·  doi:10.1016/bs.irn.2022.06.004

2021

Interactions between maternal fluoxetine exposure, the maternal gut microbiome and fetal neurodevelopment in mice
Interactions between maternal fluoxetine exposure, the maternal gut microbiome and fetal neurodevelopment in mice
Helen E. Vuong, Elena J.L. Coley, Maria Kazantsev, Michaela E. Cooke, Tomiko K. Rendon, Jorge Paramo, Elaine Y. Hsiao
Behavioural Brain Research  ·  01 Jul 2021  ·  doi:10.1016/j.bbr.2021.113353
Nurturing gut-brain research: an interview with Helen Vuong on the maternal microbiome in neurodevelopment
Nurturing gut-brain research: an interview with Helen Vuong on the maternal microbiome in neurodevelopment
Communications Biology  ·  17 Jun 2021  ·  doi:10.1038/s42003-021-02301-z

2020

Vesicular Release of GABA by Mammalian Horizontal Cells Mediates Inhibitory Output to Photoreceptors
Vesicular Release of GABA by Mammalian Horizontal Cells Mediates Inhibitory Output to Photoreceptors
Arlene A. Hirano, Helen E. Vuong, Helen L. Kornmann, Cataldo Schietroma, Salvatore L. Stella, Steven Barnes, Nicholas C. Brecha
Frontiers in Cellular Neuroscience  ·  01 Dec 2020  ·  doi:10.3389/fncel.2020.600777
The maternal microbiome modulates fetal neurodevelopment in mice
The maternal microbiome modulates fetal neurodevelopment in mice
Helen E. Vuong, Geoffrey N. Pronovost, Drake W. Williams, Elena J. L. Coley, Emily L. Siegler, Austin Qiu, Maria Kazantsev, Chantel J. Wilson, Tomiko Rendon, Elaine Y. Hsiao
Nature  ·  23 Sep 2020  ·  doi:10.1038/s41586-020-2745-3
Indigenous Microbiota Protects against Inflammation-Induced Osteonecrosis
Indigenous Microbiota Protects against Inflammation-Induced Osteonecrosis
D.W. Williams, H.E. Vuong, S. Kim, A. Lenon, K. Ho, E.Y. Hsiao, E.C. Sung, R.H. Kim
Journal of Dental Research  ·  28 Feb 2020  ·  doi:10.1177/0022034520908594

2019

Intestinal serotonin and fluoxetine exposure modulate bacterial colonization in the gut
Intestinal serotonin and fluoxetine exposure modulate bacterial colonization in the gut
Thomas C. Fung, Helen E. Vuong, Cristopher D. G. Luna, Geoffrey N. Pronovost, Antoniya A. Aleksandrova, …, Anastasia Vavilina, Julianne McGinn, Tomiko Rendon, Lucy R. Forrest, Elaine Y. Hsiao
Nature Microbiology  ·  02 Sep 2019  ·  doi:10.1038/s41564-019-0540-4
Gut Microbes Join the Social Network
Gut Microbes Join the Social Network
Helen E. Vuong, Elaine Y. Hsiao
Neuron  ·  01 Jan 2019  ·  doi:10.1016/j.neuron.2018.12.035

2018

The gut microbiota mediates reward and sensory responses associated with regimen-selective morphine dependence
The gut microbiota mediates reward and sensory responses associated with regimen-selective morphine dependence
Kevin Lee, Helen E. Vuong, David J. Nusbaum, Elaine Y. Hsiao, Christopher J. Evans, Anna M. W. Taylor
Neuropsychopharmacology  ·  10 Sep 2018  ·  doi:10.1038/s41386-018-0211-9
The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet
The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet
Christine A. Olson, Helen E. Vuong, Jessica M. Yano, Qingxing Y. Liang, David J. Nusbaum, Elaine Y. Hsiao
Cell  ·  01 Jun 2018  ·  doi:10.1016/j.cell.2018.04.027

2017

The Microbiome and Host Behavior
The Microbiome and Host Behavior
Helen E. Vuong, Jessica M. Yano, Thomas C. Fung, Elaine Y. Hsiao
Annual Review of Neuroscience  ·  25 Jul 2017  ·  doi:10.1146/annurev-neuro-072116-031347
Emerging Roles for the Gut Microbiome in Autism Spectrum Disorder
Emerging Roles for the Gut Microbiome in Autism Spectrum Disorder
Helen E. Vuong, Elaine Y. Hsiao
Biological Psychiatry  ·  01 Mar 2017  ·  doi:10.1016/j.biopsych.2016.08.024

2016

The Microbial Olympics 2016
The Microbial Olympics 2016
Michaeline B. Nelson, Alexander B. Chase, Jennifer B. H. Martiny, Roman Stocker, Jen Nguyen, …, Martin Ackermann, Chris Smillie, Diana Chien, Eric Alm, Andrew J. Jermy
Nature Microbiology  ·  26 Jul 2016  ·  doi:10.1038/nmicrobiol.2016.122

2015

Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina
Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina
Helen E. Vuong, Claudia N. Hardi, Steven Barnes, Nicholas C. Brecha
The Journal of Neuroscience  ·  02 Dec 2015  ·  doi:10.1523/JNEUROSCI.3382-15.2015
Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines
Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines
H.E. Vuong, L. Pérez de Sevilla Müller, C.N. Hardi, D.G. McMahon, N.C. Brecha
Neuroscience  ·  01 Oct 2015  ·  doi:10.1016/j.neuroscience.2015.08.060

2013

Melanopsin-expressing retinal ganglion cell loss and behavioral analysis in the Thy1-CFP-DBA/2J mouse model of glaucoma
Melanopsin-expressing retinal ganglion cell loss and behavioral analysis in the Thy1-CFP-DBA/2J mouse model of glaucoma
Qi Zhang, Helen Vuong, Xin Huang, YanLing Wang, Nicholas C. Brecha, MingLiang Pu, Jie Gao
Science China Life Sciences  ·  01 Jun 2013  ·  doi:10.1007/s11427-013-4493-1